45 Pharmacogenomics: How Genetic Testing Can Help Us

https://302.buzz/PM-WhatAreYourThoughtsWelcome to another episode of Pediatric Meltdown. My guest for today is Dr. Lisa Namerow, a Board-certified psychiatrist triple-boarded in pediatrics, child psychiatry, and general psychiatry. She has been in the pediatric healthcare space for almost 30 years, directing the consultation services to in-patient pediatrics, and the access to mental health programs for pediatricians. Her areas of research have been pharmacogenetics, and the impact of clinical pathways and standardized care for eating disorders, somatic symptoms, and related disorders, and delirium, and serves on the American Academy of Child and Adolescent Psychiatry Committee on the physically ill child.[00:01] Dr. Lisa Namerow Shares Her Story With Us Dr. Namerow shares how she became a child and adolescent psychiatrist She introduces the field of PharmacogenomicsPharmacogenomics vs. Pharmacogenetics [06:12] Genetics 101 Myths about PharmacogenomicsPharmacodynamic Genes and Pharmacokinetic GenesWhat we need to knowDr. Namerow’s analogy for genes The relationship between medicines and gene findings [16:19] Deciding if Gene Testing Can Be HelpfulWhat oncologists should know about prescribing medicinesHow a pediatrician can utilize genetic testing The screening questions to help pediatricians decide on genetic testing[26:37] Genetic Testing in ADHD, Depression, and AnxietyTalking with parents about genetic testingHow the serotonin transporter works in the body Genetics in the context of ADHD, depression, and anxiety [36:10] The Best References for Primary Care Dr. Namerow’s interesting insights about primary careHer message for clinicians that you should not miss Dr. Namerow’s message for her younger self  [46:10] Closing Segment  Our advice for all working moms out thereFinal takeaways:The role of certain relevant genes in drug responseThe industry's detailing can be misleadingThere are some very relevant gene medication pairsAn analogy about Gentamicin you should not missUsing Venlafaxine Facts about Cytochrome P450Screening questions to decide if genetic testing can be helpfulSelect medications based on evidence and guidelinesKey Quotes:“What is true is that genes do code for both the enzymes that metabolize medicines, and they also code for the proteins that are the site of the action of medication.” - Dr. Lisa Namerow“[It’s] heartbreaking that we don't have a system that cares for these kids in the way that they should be cared for, and that it falls on primary care.” - Dr. Lisa NamerowEmail [email protected] to connect with Dr. Namerow or check out Connecticut Children’s Medical Center to know more about her work. Resources Mentioned:Pharmacogenomics: An Update for Child and Adolescent PsychiatryChild Psychiatry Access Programs by state<a href="https://ki.se/en" rel="noopener...

Fecha de Publicación: 14 de julio de 2021

Duración: 58 min